Open AccessTrends in incidence, survival, and management of uveal melanoma: a population-based study of 7,516 patients from the Surveillance, Epidemiology, and End Results database (1973–2012)
Author(s) -
Krishnaraj Mahendraraj,
Christine Lau,
Injoon Lee,
Ronald S. Chamberlain
Publication year - 2016
Publication title -
clinical ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 56
eISSN - 1177-5483
pISSN - 1177-5467
DOI - 10.2147/opth.s113623
Subject(s) - medicine , incidence (geometry) , epidemiology , melanoma , malignancy , surveillance, epidemiology, and end results , concomitant , demographics , cohort , database , population , cancer registry , histopathology , pathology , demography , physics , environmental health , cancer research , sociology , computer science , optics
Uveal melanoma (UM) is the most common primary intraocular malignancy, despite comprising <5% of all melanomas. To date, relatively few case series of UM have been published. Moreover, the factors influencing survival remain largely unknown. This study sought to analyze the impact of demographics, histology, clinical presentation, and treatments on the clinical outcomes of UM in a large modern nationwide patient cohort.