Open Access<p>Mitochondrial Imbalance as a New Approach to the Study of Fibromyalgia</p>
Author(s) -
Antonio MartínezLara,
Antonio J. Sánchez Fernández,
Maripaz Jiménez-Guerrero,
Claudia Díaz-López,
Manuel de Miguel,
David Cotán,
José A. Sánchez-Alcázar
Publication year - 2020
Publication title -
open access rheumatology
Language(s) - English
Resource type - Journals
ISSN - 1179-156X
DOI - 10.2147/oarrr.s257470
Subject(s) - fibromyalgia , coenzyme q10 , pathogenesis , oxidative stress , disease , bioenergetics , medicine , bioinformatics , mitochondrion , biology , genetics
Fibromyalgia (FM) is a common chronic pain disease, whose pathogenic mechanism still remains elusive. Oxidative stress markers and impaired bioenergetics homeostasis have been proposed as relevant events in the pathogenesis of the disease. Hence, the aim of the study is to analyse the potential biomarkers of mitochondrial imbalance in FM patients along with coenzyme Q10 (CoQ10) as a possible treatment.