Open Access<p>Causal Effects of Sleep Traits on Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study</p>
Author(s) -
Huan Cai,
Jialin Liang,
Liu Z,
Fang Ting Liang,
Juan Zheng,
Jiahe Xu,
Liyi Chen,
Wen Sun,
Hao Zhang
Publication year - 2020
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s265946
Subject(s) - mendelian randomization , medicine , stroke (engine) , randomization , ischemic stroke , sleep (system call) , cardiology , bioinformatics , randomized controlled trial , gene , genetics , genetic variants , genotype , ischemia , mechanical engineering , biology , computer science , operating system , engineering
Unfavorable sleep habits have been linked with ischemic stroke in observational studies, but the causality remains unclear. The aim of this study is to investigate the potential causal role of three sleep traits, including sleep duration, insomnia, and chronotype, in ischemic stroke and its subtypes.