Open Access<p>Feasibility of Patient-Controlled Sleep with Dexmedetomidine in Treating Chronic Intractable Insomnia</p>
Author(s) -
Jian-Xiong An,
John P. Williams,
Fang Qin,
Yong Wang,
Hui Liu,
Le Shi,
Wenhao Zhang
Publication year - 2020
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s262991
Subject(s) - medicine , dexmedetomidine , insomnia , pittsburgh sleep quality index , sedation , anesthesia , premedication , bolus (digestion) , anxiety , sleep quality , psychiatry
Patient-controlled analgesia (PCA) is an "on-demand" system which allows patients to self-administer intravenous medications in small bolus doses. Based on the principles of PCA, we developed Patient-Controlled Sleep (PCSL) for chronic intractable insomnia where the traditional analgesics in PCA were replaced with dexmedetomidine (Dex), an alpha-2 agonist widely used for premedication, sedation, anxiolysis and analgesia. The purpose of this study was to assess the feasibility of the new method for the treatment of chronic intractable insomnia.