Open Access<p>Obstructive Sleep Apnea Syndrome: A Preliminary Navigated Transcranial Magnetic Stimulation Study</p>
Author(s) -
Maja Rogić Vidaković,
Joško Šoda,
Ana Jerković,
Benjamin Benzon,
Karla Bakrač,
Silvia Dužević,
Igor Vujović,
Mario Mihalj,
Renata Pecotić,
Maja Valić,
Angela Mastelić,
Maximilian Vincent Hagelien,
Marina Zmajević Schönwald,
Zoran Đogaš
Publication year - 2020
Publication title -
nature and science of sleep
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s253281
Subject(s) - transcranial magnetic stimulation , medicine , motor cortex , stimulation , obstructive sleep apnea , silent period , evoked potential , anesthesia , cardiology , audiology
An increase in resting motor threshold (RMT), prolonged cortical silent period duration (CSP), and reduced short-latency afferent inhibition (SAI), confirmed with previous transcranial magnetic stimulation (TMS), suggest decreased cortical excitability in obstructive sleep apnea syndrome (OSAS). The present study included MRI of OSAS patients for navigated TMS assessment of the RMT, as an index of the threshold for corticospinal activation at rest, and SAI as an index of cholinergic neurotransmission. We hypothesize to confirm findings on SAI and RMT with adding precision in the targeting of motor cortex in OSAS.