Open Access<p>Chronic Insomnia Is Associated with Higher Circulating Interleukin-8 in Patients with Atherosclerotic Cerebral Small Vessel Disease</p>
Author(s) -
Jihui Wang,
Xiao Chen,
Xuejiao Men,
Minhua Chen,
Jiong Tao,
Zhengqi Lu
Publication year - 2020
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s239030
Subject(s) - medicine , polysomnography , gastroenterology , pathological , cytokine , insomnia , tumor necrosis factor alpha , pathogenesis , apnea , psychiatry
Chronic inflammatory responses and leukocyte infiltration are classical pathological features of cerebral small vessel disease (CSVD). To date, limited evidence of a relationship between chronic insomnia and inflammatory responses in patients with CSVD has been uncovered. The purpose of the present study was to investigate the potential relationship between chronic insomnia and pro-inflammatory cytokine levels in patients with atherosclerotic CSVD (A-CSVD).