Open AccessIntramyocellular Lipids, Insulin Resistance, and Functional Performance in Patients with Severe Obstructive Sleep Apnea
Author(s) -
Meng-Yueh Chien,
PeiLin Lee,
ChihWei Yu,
Shwu Yuan Wei,
Tiffany Ting-Fang Shih
Publication year - 2020
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s232554
Subject(s) - medicine , insulin resistance , obstructive sleep apnea , endocrinology , body mass index , dyslipidemia , insulin , obesity
An increasing number of studies have linked the severity of obstructive sleep apnea (OSA) with metabolic dysfunction. However, little is known about the lipid compartments (intramyocellular [IMCL] and extramyocellular [EMCL] lipids) inside the musculature in these patients. The present study was designed to investigate the IMCL and EMCL, biochemical data, and functional performance in patients with severe OSA, and to examine the correlations between intramuscular lipid contents and test variables.