Open AccessDiamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
Author(s) -
Malwina Sosnowska,
Marta Kutwin,
Barbara Strojny,
Mateusz Wierzbicki,
Dominik Cysewski,
Jarosław Szczepaniak,
Mateusz Ficek,
P. Koczoń,
Sławomir Jaworski,
A. Chwalibog,
Ewa Sawosz
Publication year - 2021
Publication title -
nanotechnology, science and applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.051
H-Index - 28
ISSN - 1177-8903
DOI - 10.2147/nsa.s322766
Subject(s) - cancer cell , cell growth , flow cytometry , cell culture , liver cancer , cell , chemistry , cell cycle , hepatocellular carcinoma , biophysics , materials science , nanotechnology , cancer , microbiology and biotechnology , cancer research , biology , biochemistry , medicine , genetics
Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation.