Open AccessOptimization of an Intranasal Route for the Delivery of Human Neural Stem Cells to Treat a Neonatal Hypoxic-Ischemic Brain Injury Rat Model
Author(s) -
Shan Lu,
Li K,
Yi Yang,
Q Wang,
Yu Yan,
Z Wang,
Z Luan
Publication year - 2022
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s350586
Subject(s) - nasal administration , medicine , transplantation , neural stem cell , stem cell , hypoxia (environmental) , pathology , pharmacology , surgery , biology , microbiology and biotechnology , chemistry , organic chemistry , oxygen
Stem cell administration via the intranasal route has shown promise as a new therapy for hypoxic-ischemic encephalopathy (HIE). In this study, we aimed to improve the intranasal delivery of stem cells to the brain.