Open AccessThe Combination of Serum BDNF, Cortisol and IFN-Gamma Can Assist the Diagnosis of Major Depressive Disorder
Author(s) -
Suzhen Chen,
Yuqun Zhang,
Yonggui Yuan
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s322078
Subject(s) - medicine , hamd , logistic regression , major depressive disorder , stepwise regression , antidepressant , brain derived neurotrophic factor , depression (economics) , rating scale , neurotrophic factors , anxiety , hamilton anxiety rating scale , oncology , area under the curve , psychiatry , receptor , psychology , developmental psychology , macroeconomics , amygdala , economics
Misdiagnosis and ineffective treatment are common in major depressive disorder (MDD) in current clinical practice, while the combination of various serum proteins may assist the correct diagnosis. The study aimed to explore whether the combination of serum inflammatory, stress, and neurotrophic factors could be helpful for the diagnosis of MDD and to investigate the predictors associated with early symptom improvements.