Open AccessCariprazine: Patients with Treatment-Resistant Schizophrenia
Author(s) -
Thomas Aubel
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s315653
Subject(s) - medicine , psychosocial , schizophrenia (object oriented programming) , quality of life (healthcare) , psychological intervention , psychiatry , antipsychotic , affect (linguistics) , clinical psychology , psychology , nursing , communication
Schizophrenia is a chronic relapsing and remitting disorder associated with significant impairments in social and vocational functioning and a shortened lifespan, and it is a disabling psychiatric brain syndrome whose phenotype is characterized by three core symptom domains: positive symptoms, such as delusions and hallucinations, negative symptoms, which include lack of motivation and social withdrawal, and cognitive impairment. Moreover, patients with schizophrenia have severe problems with personal and social relations which affect their quality of life. Antipsychotic medications in conjunction with psychosocial interventions can help patients achieve recovery. Here are described three clinical cases of schizophrenic patients treated with cariprazine for inadequate response to a previous treatment. The purpose of this clinical series is to give useful information for the use of cariprazine in clinical practice.