Open AccessHigh Mobility Group Box 1/Toll-like Receptor 4 Signaling Increases GABRB3 Expression in Alcohol Exposure
Author(s) -
Guoqiang Sun,
Xunzhong Qi,
Wei Wang,
Xintong Li,
Chunxiong Luo,
Shunjie Bai,
Shaohua Xu,
Xiaogang Zhong,
ChengLong Huang,
Xiaofeng Zhu,
ZhiZhen Huang
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s306242
Subject(s) - microarray , striatum , microarray analysis techniques , prefrontal cortex , gene expression , medicine , hmgb1 , tlr4 , receptor , endocrinology , pharmacology , dopamine , gene , biology , biochemistry , psychiatry , cognition
Prefrontal cortex (PFC) and striatal neurotransmitter homeostasis is affected by alcohol dependence. In this study, the microarray dataset from the Gene Expression Omnibus (GEO) database were downloaded. The prefrontal and striatum data were cross-analyzed to reveal the co-effects of alcohol dependence on the two brain regions of mice.