Open AccessNeuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice
Author(s) -
Zhen-Nian Zhang,
Hui Zhang,
Changpeng Chen,
Yan Liang,
Lili Tang,
SuLei Wang,
Chengcheng Xu,
Hui Yang,
Jing-Si Zhang,
Yang Zhao
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s299685
Subject(s) - mptp , neuroprotection , superoxide dismutase , substantia nigra , medicine , glial cell line derived neurotrophic factor , tyrosine hydroxylase , neurotrophic factors , endocrinology , western blot , oxidative stress , dopamine , glutathione peroxidase , glutathione , parkinson's disease , hindlimb , pharmacology , biochemistry , chemistry , dopaminergic , enzyme , disease , gene , receptor
To explore the neuroprotective effect and the related mechanisms of echinacoside (ECH) in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD) mice.