Open Access
Correlations Between Working Memory Impairment and Neurometabolites of the Prefrontal Cortex in Drug-Naive Obsessive-Compulsive Disorder
Author(s) -
Jihui Yue,
Shuming Zhong,
Aimin Luo,
Shunkai Lai,
Tingting He,
Yuchong Luo,
Ying Wang,
Yiliang Zhang,
Shiyi Shen,
Hui Huang,
Shi Wu Wen,
Yanbin Jia
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s296488
Subject(s) - medicine , stroop effect , drug naïve , working memory , audiology , memory span , neuropsychology , prefrontal cortex , creatine , trail making test , choline , psychiatry , drug , cognition
This study aimed to investigate the mechanism of working memory (WM) impairment in drug-naive obsessive-compulsive disorder (OCD) by using neuropsychological tests and proton magnetic resonance spectroscopy ( 1 H-MRS).