Open AccessMiR-101 Protects Against the Cerebral I/R Injury Through Regulating JAK2/STAT3 Signaling Pathway
Author(s) -
Xiaowang Guo,
X. Y. Shen,
Zhijun Yong
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s292471
Subject(s) - apoptosis , medicine , gene silencing , viability assay , downregulation and upregulation , western blot , ischemia , in vivo , microrna , reperfusion injury , stat3 , pharmacology , brain ischemia , cancer research , biology , biochemistry , gene , microbiology and biotechnology
Ischemic stroke is a devastating disease with very limited therapeutics. Although miR-101 has been reported to play crucial roles in various human diseases, its role in ischemic stroke remains unclear.