Open AccessThe Combination of Insulin Resistance and Serum Interleukin-1β Correlates with Post-Stroke Depression in Patients with Acute Ischemic Stroke
Author(s) -
XiaoYi Yi,
Xiangyang Zhu,
Yong Zhou,
Dongmei Zhang,
Mengmeng Li,
Yuting Zhu,
Xiaoming Guo
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s291164
Subject(s) - medicine , insulin resistance , depression (economics) , logistic regression , stroke (engine) , receiver operating characteristic , post stroke depression , anxiety , prospective cohort study , mood , homeostatic model assessment , gastroenterology , insulin , psychiatry , mechanical engineering , treatment and control groups , engineering , economics , macroeconomics
Previous studies have shown that insulin resistance and inflammation may be associated with the pathophysiological mechanisms of mood disorders. Here, we investigated whether homeostatic model assessment of insulin resistance (HOMA-IR) and serum interleukin-1β (IL-1β) in acute ischemic stroke patients might be associated with post-stroke depression (PSD).