Open AccessAddition of Aβ42 to Total Cerebral Small Vessel Disease Score Improves the Prediction for Cognitive Impairment in Cerebral Small Vessel Disease Patients
Author(s) -
Jianping Liu,
Weihua Zhao,
Qinghong Gui,
Ying Zhang,
Zaiyu Guo,
Wei Liu
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s289357
Subject(s) - medicine , logistic regression , univariate analysis , receiver operating characteristic , mann–whitney u test , gastroenterology , diabetes mellitus , hyperlipidemia , disease , stepwise regression , blood test , area under the curve , multivariate analysis , endocrinology
To investigate the associations between concentrations of Aβ 40 and Aβ 42 and vascular cognitive impairment (VCI) in cerebral small vessel disease (CSVD) patients and evaluate the value of combination of levels of Aβ 40 or Aβ 42 and the total CSVD score in predicting VCI.