Open Access<p>Association of Serum Kynurenine Levels and Neural Networks in Patients with First-Episode, Drug-Naïve Major Depression: A Source-Based Morphometry Study</p>
Author(s) -
Naomichi Okamoto,
Keita Watanabe,
LeHoa Ngyuyen,
Atsuko Ikenouchi,
Taro Kishi,
Nakao Iwata,
Shingo Kakeda,
Yukunori Korogi,
Reiji Yoshimura
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s279622
Subject(s) - kynurenine , default mode network , medicine , depression (economics) , psychiatry , kynurenic acid , glutamate receptor , tryptophan , biochemistry , cognition , chemistry , amino acid , economics , macroeconomics , receptor
The kynurenine (KYN) pathway can directly or indirectly influence cerebral volume and neural integrity in patients with major depression (MD). The aim of the present study was to investigate neural network systems and the KYN pathway in patients with first-episode, drug-naïve MD.