Open AccessSchisandrin Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in Mouse Models of Alzheimer’s Disease
Author(s) -
Quan Li,
Qi Wang,
Guan Hong-quan,
Yanmin Zhou,
Li Liu
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s279147
Subject(s) - pyroptosis , inflammasome , medicine , nlrp1 , caspase 1 , disease , neuroscience , pharmacology , caspase , apoptosis , immunology , programmed cell death , inflammation , biochemistry , biology
In recent years, schisandrin (SCH) was proved to improve Alzheimer's Disease (AD). The aim of our study is to explore the effect of SCH on neuronal pyroptosis in the disease.