Open Access<p>NR4A2 Exacerbates Cerebral Ischemic Brain Injury via Modulating microRNA-652/Mul1 Pathway</p>
Author(s) -
Qiandong Liu,
Qinglin Dong
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s265601
Subject(s) - apoptosis , cell cycle , biology , transcription factor , microrna , psychological repression , cancer research , microbiology and biotechnology , medicine , gene expression , gene , biochemistry
Nuclear receptor subfamily group A member 2 (NR4A2), a transcription factor, was suggested to be involved in the pathogenesis of ischemic stroke. Nevertheless, the specific role of NR4A2 in ischemic brain injury has yet to be elucidated. Our aim was to probe the mechanisms behind the repression of microRNA (miRNA) expression resulting from NR4A2 regulation in ischemic brain injury.