Open Access<p>Expression Profiles of Long Noncoding RNAs in Mice with High-Altitude Hypoxia-Induced Brain Injury Treated with <em>Gymnadenia conopsea</em> (L.) R. Br.</p>
Author(s) -
Yongcang Zhang,
Lan Liu,
Cuiting Liang,
Lei Zhou,
Lushi Tan,
Yujin Zong,
Lili Wu,
Tonghua Liu
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s246504
Subject(s) - hypoxia (environmental) , medicine , long non coding rna , microarray , cancer research , microbiology and biotechnology , gene expression , biology , gene , downregulation and upregulation , genetics , chemistry , oxygen , organic chemistry
The unique geographical environment at high altitudes may cause a series of diseases, such as acute altitude reaction, cerebral edema, and pulmonary edema. Gymnadenia conopsea (L.) R. Br. has been reported to have an effect on high-altitude hypoxia. However, the molecular mechanism, especially the expression of long noncoding RNAs (lncRNAs), is not yet clear.