Open AccessIrreversible Primary Visual Cortex Impairment in a Mouse Model of High-Risk Schizophrenia
Author(s) -
Xinying Chen,
Ce Chen,
JiaXun Feng,
Yong Xu,
Wenqiang Wang,
Xiaodong Lin,
Deguo Jiang,
Xueqin Song,
Xiangyang Gao,
Hongjun Tian,
Chuanjun Zhuo,
Jingliang Zhang
Publication year - 2021
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s246163
Subject(s) - schizophrenia (object oriented programming) , visual cortex , medicine , prepulse inhibition , antipsychotic , neuroscience , risperidone , psychiatry , psychology
Although visual deficits can be observed at any stage of schizophrenia, few studies have focused on visual cortex alterations in individuals at high risk of schizophrenia. This study aimed to investigate the pathological changes of the primary visual cortex in a prenatal mouse model of MK801-induced high-risk schizophrenia.