Open Access<p>Atrophic Corpus Callosum Associated with Altered Functional Asymmetry in Major Depressive Disorder</p>
Author(s) -
Shuhua Ran,
Zhiwei Zuo,
Chang Ming Li,
Xuntao Yin,
Wei Qu,
Qiusha Tang,
Yao Wang,
Yanshu Shi,
Haitao Li
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s245078
Subject(s) - corpus callosum , precuneus , medicine , gyrus , neuroscience , middle temporal gyrus , middle frontal gyrus , superior frontal gyrus , magnetic resonance imaging , major depressive disorder , default mode network , functional magnetic resonance imaging , psychology , anatomy , radiology , cognition
Impairments in intra- and inter-hemispheric information transfer circuits have been reported in patients with major depressive disorder (MDD). However, the specific anomalous connection (intra- and/or inter-hemispheric) and hemisphere (left and/or right) in which this connection plays a more dominant role in the pathogenic mechanism underlying MDD are still poorly understood.