Open Access<p>MicroRNA-382-5p Targets Nuclear Receptor Subfamily 3 Group C Member 1 to Regulate Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats</p>
Author(s) -
Shuqian Li,
Hong Ma,
Yuan Xu,
Xiaomei Zhou,
Yiwen Wan,
Shangjie Chen
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s243920
Subject(s) - hippocampus , medicine , behavioural despair test , depression (economics) , microrna , endocrinology , pathogenesis , glucocorticoid receptor , tropomyosin receptor kinase b , affect (linguistics) , glucocorticoid , receptor , psychology , biology , neurotrophic factors , genetics , antidepressant , gene , economics , macroeconomics , communication
Depression is an emotional disorder characterized by depression, lack of pleasure, and cognitive and sleep disorders. It is a systemic disease with a complex pathogenesis. In this study, we will be focused to investigate their associations and the exact functional mechanisms of miR-382-5p and NR3C1 in depression.