Open Access<p>Gene–Environment Interactions in Major Mental Disorders in the Czech Republic</p>
Author(s) -
Klára Látalová,
Omar Šerý,
Kristyna Hosakova,
Ladislav Hosák
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s238522
Subject(s) - medicine , population , anxiety , schizophrenia (object oriented programming) , psychiatry , mood disorders , major depressive disorder , bipolar disorder , affect (linguistics) , mental illness , depression (economics) , psychological intervention , clinical psychology , prevalence of mental disorders , mood , mental health , psychology , environmental health , communication , economics , macroeconomics
Mental disorders affect about one-third of the human population, are typically chronic and significantly decrease the quality of life. Presently, the treatment of mental illnesses is far from adequate with a substantial proportion of the patients being pharmacoresistant and suffering from relapses. One of the reasons for this complicated situation is that we do not precisely know about the causes of mental disorders, so their treatment cannot be causal. The etiology of a mental disorder is typically based on a combination of molecular (genetic) and environmental factors.