Open Access<p>Stigmasterol Exerts Neuro-Protective Effect Against Ischemic/Reperfusion Injury Through Reduction Of Oxidative Stress And Inactivation Of Autophagy</p>
Author(s) -
Jiadong Sun,
Xuemei Li,
Junling Liu,
Xin Pan,
Qianqian Zhao
Publication year - 2019
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s220224
Subject(s) - ampk , autophagy , medicine , stigmasterol , pi3k/akt/mtor pathway , oxidative stress , reperfusion injury , protein kinase a , keap1 , pharmacology , kinase , signal transduction , ischemia , endocrinology , microbiology and biotechnology , biochemistry , apoptosis , chemistry , biology , chromatography , gene , transcription factor
Stroke remains the primary cause of pain, suffering, and death in patients. One of the major thrusts in stroke therapy is to find an effective prevention strategy. Objectives of this study are to testify the neuro-protection effect of stigmasterol in ischemic/reperfusion injury model.