Open Access<p>Apolipoprotein E e4 allele is associated with extrapyramidal symptoms in Alzheimer’s disease</p>
Author(s) -
YangPei Chang,
Mei-Chuan Chou,
Chiou-Lian Lai,
Isabel Chien,
YuanHan Yang
Publication year - 2019
Publication title -
neuropsychiatric disease and treatment
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s207050
Subject(s) - medicine , apolipoprotein e , allele , disease , extrapyramidal symptoms , bioinformatics , genetics , psychiatry , gene , schizophrenia (object oriented programming) , antipsychotic , biology
Extrapyramidal symptoms (EPS) are not uncommon in Alzheimer's disease (AD). As apolipoprotein E(APOE) e4 allele is a major risk factor for late-onset AD, we intend to examine the association between APOE genotype and the development of EPS in AD.