Open AccessMoving Toward a Multimodal Analgesic Regimen for Acute Sickle Cell Pain with Non-Opioid Analgesic Adjuncts: A Narrative Review
Author(s) -
Martha O Kenney,
Wally R. Smith
Publication year - 2022
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s343069
Subject(s) - medicine , analgesic , vaso occlusive crisis , intensive care medicine , acute pain , narrative review , disease , pain medicine , multimodal therapy , chronic pain , gold standard (test) , opioid , regimen , physical therapy , anesthesia , sickle cell anemia , anesthesiology , receptor
Sickle cell disease (SCD) is an inherited hemoglobinopathy with potential life-threatening complications that affect millions of people worldwide. Severe and disabling acute pain, referred to as a vaso-occlusive crisis (VOC), is a fundamental symptom of the disease and the primary driver for acute care visits and hospitalizations. Despite the publication of guidelines for VOC management over the past decade, management of VOCs remains unsatisfactory for patients and providers.