Open AccessDeep Neuromuscular Blockade Combined with Low Pneumoperitoneum Pressure for Nociceptive Recovery After Major Laparoscopic Gastrointestinal Surgery: Study Protocol for a Randomized Controlled Trial
Author(s) -
Yu-qin Long,
Xisheng Shan,
Xiaomei Feng,
Hong Liu,
Fuhai Ji,
Ke Peng
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s336870
Subject(s) - medicine , anesthesia , postoperative nausea and vomiting , randomized controlled trial , pneumoperitoneum , laparoscopic surgery , neuromuscular blockade , analgesic , laparoscopy , surgery , nausea
Patients undergoing major laparoscopic surgery often experience significant pain and postoperative nausea and vomiting (PONV). Deep neuromuscular block (NMB) improves surgical conditions and facilitates the application of low intra-abdominal pressure (IAP), which may be beneficial for these patients. This study is designed to determine the effects of deep NMB combined with low IAP, as compared to moderate NMB combined with standard IAP, on patients' nociceptive recovery after major laparoscopic gastrointestinal surgery.