Open AccessGene Expression Profiling of Contralateral Dorsal Root Ganglia Associated with Mirror-Image Pain in a Rat Model of Complex Regional Pain Syndrome Type-I
Author(s) -
Huimin Nie,
Boyu Liu,
Chengyu Yin,
Ruixiang Chen,
Jie Wang,
Danyi Zeng,
Yan Tai,
Jingdun Xie,
Dongwei He
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s322372
Subject(s) - nociceptor , medicine , chronic pain , nociception , neuroscience , pathogenesis , neuropathic pain , bioinformatics , pathology , anesthesia , biology , receptor , psychiatry
Mirror-image pain (MIP), which develops from the healthy body region contralateral to the actual injured site, is a mysterious pain phenomenon accompanying many chronic pain conditions, such as complex regional pain syndrome (CRPS). However, the pathogenesis of MIP still remains largely unknown. The purpose of this study is to perform an expression profiling to identify genes related to MIP in an animal model of CRPS-I.