Open AccessExpression of Substance P and Nerve Growth Factor in Degenerative Long Head of Biceps Tendon in Patients with Painful Rotator Cuff Tear
Author(s) -
Masashi Izumi,
Yoshifumi Harada,
Yukihiro Kajita,
Yoshitaka Muramatsu,
Toru Morimoto,
Yutaka Morisawa,
Yusuke Iwahori,
Masahiko Ikeuchi
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s320811
Subject(s) - medicine , rotator cuff , biceps , nerve growth factor , substance p , tenotomy , visual analogue scale , gastroenterology , surgery , tendon , neuropeptide , receptor
Degenerative long head of biceps tendon (LHBT) has been recognized as a notable pain source in patients with rotator cuff tear (RCT). Tenotomy or tenodesis of LHBT is frequently indicated together with arthroscopic rotator cuff repair (ARCR) aiming for complete pain relief; however, it has not been fully investigated whether resected LHBT is really a source of pain. The purpose of this study was to investigate expression levels of pain-associated mediators in LHBT and its association with preoperative pain profiles.