Open AccessS100A4 in Spinal Substantia Gelatinosa from Dorsal Root Ganglia Modulates Neuropathic Pain in a Rodent Spinal Nerve Injury Model
Author(s) -
Xin Jiang,
Weigang Zhao,
Tiantian Zhao,
Mei Yang,
Hongbin Yuan,
Jun Qian,
Zhenghua Xiang
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s293462
Subject(s) - neuropathic pain , medicine , dorsal root ganglion , spinal cord , nerve injury , spinal nerve , neuroscience , immunofluorescence , rat model , anesthesia , nerve root , dorsum , antibody , anatomy , immunology , biology , psychiatry
To detect the spatio-temporal expression of S100A4 in a spinal nerve ligation (SNL) rat model. Also to figure out which other molecules directly interact with S100A4 to explore the possible mechanisms which might be involved in neuropathic pain.