Open AccessExosome-Encapsulated microRNA-127-3p Released from Bone Marrow-Derived Mesenchymal Stem Cells Alleviates Osteoarthritis Through Regulating CDH11-Mediated Wnt/β-Catenin Pathway
Author(s) -
Jian Dong,
Li Li,
Xing Fang,
Mousheng Zang
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s291472
Subject(s) - microvesicles , exosome , mesenchymal stem cell , wnt signaling pathway , microrna , microbiology and biotechnology , medicine , cancer research , catenin , osteoarthritis , signal transduction , biology , pathology , gene , biochemistry , alternative medicine
Exosome-encapsulated microRNAs (miRNAs) are being considered as either diagnostic or predictive markers in different types of diseases. Here, we discussed the effects of exosome-encapsulated miR-127-3p from bone marrow-derived mesenchymal stem cells (BM-MSCs) on osteoarthritis (OA).