Open AccessDirect and Indirect Pathways for Health-Related Quality of Life Change from Pain Improvement in Neuropathic Pain Patients with Spine Diseases: Path Analysis with Structural Equation Modeling Using Non-Interventional Study Results of Pregabalin
Author(s) -
Toshihiko Taguchi,
Kazutaka Nozawa,
Shigeki Zeniya,
Tatsunori Murata,
Thomas Laurent,
Toshio Hirano,
Koichi Fujii
Publication year - 2021
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s289396
Subject(s) - medicine , neuropathic pain , physical therapy , quality of life (healthcare) , pittsburgh sleep quality index , chronic pain , affect (linguistics) , physical medicine and rehabilitation , cognition , psychiatry , sleep quality , anesthesia , nursing , linguistics , philosophy
Chronic low back pain or chronic cervical pain often has a neuropathic pain (NeP) component and patients with these conditions complain of sleep deprivation, loss of physical function, and reduced productivity due to pain. The objective of this study was to clarify the pathway by which pain, sleep disturbance due to pain, and physical function status influence QOL measures in chronic low back pain patients with NeP associated with lumbar spine diseases (CLBP-NeP) and in chronic cervical pain patients with NeP associated with cervical spine diseases (CCP-NeP).