Open AccessVagus Nerve Stimulation Transiently Mitigates Chemotherapy-Induced Peripheral Neuropathy in Rats
Author(s) -
Ran Zhang,
Yu Gan,
Jun Li,
Yi Feng
Publication year - 2020
Publication title -
journal of pain research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s281190
Subject(s) - medicine , vagus nerve stimulation , stimulation , anesthesia , paclitaxel , vagus nerve , saline , peripheral neuropathy , chemotherapy , endocrinology , diabetes mellitus
Chemotherapy-induced peripheral neuropathy is a severe side effect of chemotherapeutic agents. Vagus nerve stimulation attenuates neuroinflammation by activating the cholinergic anti-inflammatory pathway and thus may attenuate CIPN.