Open Access<p>Decreased MiR-485-5p Contributes to Inflammatory Pain Through Post-Transcriptional Upregulation of ASIC1 in Rat Dorsal Root Ganglion</p>
Author(s) -
Meijie Xu,
Rui Wu,
Ling Ling Zhang,
Hongyan Zhu,
GuangYin Xu,
Wenxia Qian,
Pingan Zhang
Publication year - 2020
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s279902
Subject(s) - dorsal root ganglion , downregulation and upregulation , medicine , acid sensing ion channel , neuropathic pain , pharmacology , endocrinology , microbiology and biotechnology , receptor , ion channel , dorsum , anatomy , biochemistry , biology , gene
Inflammatory pain is the most common type of pain treated clinically. However, the currently available treatments for inflammatory pain have limited effects and can cause severe side effects. The aim of this study is to describe the effect of miRNA-485-5p on osteoarthritis-related inflammatory pain.