Open Access<p>DNA Microarray Analysis of Differential Gene Expression in the Dorsal Root Ganglia of Four Different Neuropathic Pain Mouse Models</p>
Author(s) -
Hiroyuki Yokoyama,
Takashi Hirai,
Tetsuya Nagata,
Mitsuhiro Enomoto,
Hidetoshi Kaburagi,
Li Leiyo,
Takayuki Motoyoshi,
Toshitaka Yoshii,
Atsushi Okawa,
Takanori Yokota
Publication year - 2020
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s272952
Subject(s) - sni , neuropathic pain , medicine , dorsal root ganglion , nerve injury , allodynia , microarray analysis techniques , knockout mouse , chronic pain , hyperalgesia , pharmacology , anesthesia , gene expression , receptor , gene , biology , anatomy , nociception , genetics , biochemistry , dorsum , psychiatry , hydrolysis , acid hydrolysis
Pathological stimuli or injury to the peripheral nervous system can trigger neuropathic pain with common clinical features such as allodynia and hypersensitivity. Although various studies have identified molecules or genes related to neuropathic pain, the essential components are still unclear. Therefore, in this study, we investigated the molecular and genetic factors related to neuropathic pain.