Open Access<p>Usefulness of a Double-Blind Placebo-Controlled Response Test to Demonstrate Rapid Onset Analgesia with Phenytoin 10% Cream in Polyneuropathy</p>
Author(s) -
David J Kopsky,
Alexander F.J.E. Vrancken,
Jan M Keppel Hesselink,
Ruben P A van Eijk,
Nicolette C. Notermans
Publication year - 2020
Publication title -
journal of pain research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 49
ISSN - 1178-7090
DOI - 10.2147/jpr.s243434
Subject(s) - medicine , placebo , analgesic , anesthesia , phenytoin , neuropathic pain , double blind , epilepsy , alternative medicine , pathology , psychiatry
Topical analgesics are an upcoming treatment option for neuropathic pain. In this observational study, we performed a double-blind placebo-controlled response test (DOBRET) in patients with polyneuropathy to determine the personalized analgesic effect of phenytoin 10% cream.