Open AccessTfh Exosomes Derived from Allergic Rhinitis Promote DC Maturation Through miR-142-5p/CDK5/STAT3 Pathway
Author(s) -
Zhen-Xiao Teng,
Xinming Zhou,
Run-Tong Xu,
Fulong Zhu,
Xin Bing,
Ning Guo,
Lei Shi,
Wenwen Qi,
Chengcheng Liu,
Mengna Xia
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s365217
Subject(s) - microvesicles , flow cytometry , microbiology and biotechnology , microrna , transfection , biology , signal transduction , gene knockdown , reporter gene , chemistry , immunology , gene , gene expression , genetics
Dendritic cells (DCs) play an important role in allergen signal presentation. Many studies showed that follicular helper T cells (Tfhs) are related to allergic rhinitis (AR). However, the relationship between Tfhs and DCs and the mechanism of their interaction with AR remain unclear.