Open AccessThe Construction of ITP Diagnostic Modeling Based on the Expressions of Hub Genes Associated with M1 Polarization of Macrophages
Author(s) -
Ming-Jing Wang,
Ying Song,
Xueyi Guo,
Diu Wei,
Xianlong Cao,
Yan Sun,
Yan Xu,
Xiaomei Hu
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s364414
Subject(s) - immune system , receiver operating characteristic , biology , immunology , kegg , gene , gene expression , computational biology , genetics , medicine , transcriptome
Primary immune thrombocytopenia (ITP) is an immune disease with a diagnosis of exclusion, since no validated biomarkers have been identified. In this study, we explored biomarkers associated with the development of ITP from an immune perspective to inform the clinical diagnosis.