Open AccessClinical Values and Underlying Mechanism Analysis of Serum miR-455-5p in Carotid Artery Stenosis
Author(s) -
Bin Zhu,
Wei Liu,
Qiang Xu,
Hongliang Liu
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s362774
Subject(s) - medicine , stenosis , logistic regression , proportional hazards model , receiver operating characteristic , asymptomatic , cardiology , hazard ratio , odds ratio , risk factor , gastroenterology , confidence interval
Carotid artery stenosis (CAS) is a leading cause of cerebral infarction, its early diagnosis and intervention are necessary. In light of the important role of microRNAs (miRNAs) in cerebrovascular disease, this study aimed to investigate the expression pattern and clinical significance of serum miR-455-5p in the onset and development of CAS, as well as its underlying mechanism.