Open AccessAdiponectin Ameliorates Hyperglycemia-Induced Retinal Endothelial Dysfunction, Highlighting Pathways, Regulators, and Networks
Author(s) -
Sumbul Bushra,
Duaa W. AlSadeq,
Redwana Bari,
Afifah Sahara,
Amina Fadel,
Nasser Rizk
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s358594
Subject(s) - adiponectin , angiogenesis , microbiology and biotechnology , signal transduction , biology , medicine , endocrinology , chemistry , cancer research , diabetes mellitus , insulin resistance
The pathophysiology of diabetic retinopathy (DR) is multifaced. A low level of circulating adiponectin (APN) in type 2 diabetes is associated with microvasculature complications, and its role in the evolution of DR is complex.