Open AccessSystematic Analysis of Chemokines Reveals CCL18 is a Prognostic Biomarker in Glioblastoma
Author(s) -
Wenqing Gao,
Yuanyuan Li,
Teng Zhang,
Jianglong Lu,
Jiasong Pan,
Qi Qi,
Siqi Dong,
Xiangjun Chen,
Zhi-Peng Su,
Jixi Li
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s357787
Subject(s) - glioma , chemokine , ccl18 , cxcl5 , cxcl1 , biology , ccl7 , cancer research , chemokine receptor , immunology , immune system
Glioblastoma (GBM) is the most common and aggressive brain tumor in adults, in which chemokines are often upregulated and may play pivotal roles in their development and progression. Chemokines are a large subfamily of cytokines with leukocyte chemotactic activities involved in various tumor progression. However, gene expression patterns of the chemokines on a global scale were not known in GBM.