Open AccessThe Role of Bone Morphogenetic Protein 4 in Microglial Polarization in the Process of Neuropathic Pain
Author(s) -
Changqing Liu,
Qi Sun,
Junmei Xu,
Weiyun Shen,
Hui Li,
Lin Yang
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s356531
Subject(s) - noggin , bone morphogenetic protein 4 , neuropathic pain , bone morphogenetic protein , medicine , endocrinology , blot , flow cytometry , chemistry , pharmacology , immunology , biochemistry , gene
Neuropathic pain (NP) is known to be highly correlated with microglial polarization, of which the regulatory mechanism remains to be elucidated. Here, the aim of this study is to further investigate the relationship between bone morphogenetic protein 4 (BMP4) and microglial polarization in the process of NP.