Open AccessIdentification and Validation of Autophagy-Related Genes in Sepsis-Induced Acute Respiratory Distress Syndrome and Immune Infiltration
Author(s) -
Mengfei Sun,
Qianqian Yang,
Chunling Hu,
Hengchao Zhang,
Xing Liu
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s355225
Subject(s) - immune system , sepsis , immune dysfunction , acute respiratory distress , immunology , autophagy , gene , respiratory distress , medicine , biology , genetics , lung , surgery , apoptosis
Autophagy-related genes (ARGs) play an important role in the pathophysiology processes of sepsis-induced acute respiratory distress syndrome (ARDS). However, expression profiles of ARGs have rarely been used to explore the relationship between autophagy and sepsis-induced ARDS. Therefore, we aim to identify and validate the potential ARGs of sepsis-induced ARDS through bioinformatics analysis and experiment validation.