Open AccessCD11b-Based Pre-Targeted SPECT/CT Imaging Allows for the Detection of Inflammation in Aortic Aneurysm
Author(s) -
Xiaobin Zhou,
Kai Zhu,
Yiqiu Zhang,
Yang Ming,
Dai Shi,
Hui Tan,
Bitao Xiang,
Shufeng Zhu,
Dengfeng Cheng,
Hao Lai,
Chunsheng Wang,
Guobing Liu
Publication year - 2022
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s350593
Subject(s) - single photon emission computed tomography , in vivo , emission computed tomography , integrin alpha m , nuclear medicine , medicine , positron emission tomography , radiology , chemistry , biology , receptor , microbiology and biotechnology
To investigate the feasibility of a pre-targeted imaging strategy based on the cycloaddition between 1,2,4,5-terazine (Tz) and trans-cyclooctene (TCO) for evaluating CD11b expression in inflammatory aortic aneurysm (AA) using single photon emission computed tomography/computed tomography (SPECT/CT).