Open AccessUpregulation of TMEM45A Promoted the Progression of Clear Cell Renal Cell Carcinoma in vitro
Author(s) -
Huiming Jiang,
Haibin Chen,
Pei Wan,
Meng Liang,
Nanhui Chen
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s341596
Subject(s) - clear cell renal cell carcinoma , cancer research , gene knockdown , downregulation and upregulation , biology , cell growth , cancer , renal cell carcinoma , cell , epithelial–mesenchymal transition , apoptosis , medicine , oncology , gene , biochemistry , genetics
Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive type of primary kidney cancer worldwide. Transmembrane protein 45A (TMEM45A) has been reported to be closely associated with the progression of several cancers. However, the role of TMEM45A in ccRCC remains unclear. Our study intended to explore the potential role of TMEM45A in ccRCC.