Open AccessA Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population
Author(s) -
ShouEn Wu,
WeiLiang Chen
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s338724
Subject(s) - sarcopenia , single nucleotide polymorphism , genome wide association study , genotype , genetic association , medicine , population , bioinformatics , genetics , oncology , biology , gene , environmental health
A genome-wide association study (GWAS) of sarcopenia unraveled the importance of genetic contribution to decline in muscle. The current study investigated sarcopenia-related single nucleotide polymorphisms (SNPs) in Asian older adults, and further constructed a genotype score that tests the combined effect of these SNPs on risk of sarcopenia.