Open AccessPotentially Functional microRNA-mRNA Regulatory Networks in Intestinal Ischemia-Reperfusion Injury: A Bioinformatics Analysis
Author(s) -
Zhongg Jiang,
Song Chen,
Lin Zhang,
Jie Shen,
Ming Zhong
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s328732
Subject(s) - microrna , kegg , biology , messenger rna , regulation of gene expression , gene regulatory network , reperfusion injury , gene expression , gene , computational biology , bioinformatics , genetics , ischemia , gene ontology , medicine
Intestinal ischemia-reperfusion (II/R) injury is a common clinical complication associated with high mortality, for which microRNA (miRNA) drives potentially its pathophysiological progression. MiRNAs regulate different messenger RNAs (mRNAs). However, the regulatory network between miRNAs and mRNAs in intestinal ischemia-reperfusion injury is elusive.