Open AccessTranscription Coactivator BCL3 Acts as a Potential Regulator of Lipid Metabolism Through the Effects on Inflammation
Author(s) -
Shuo Zhang,
Jingtao Gao,
Shibo Liu,
Yu Lu,
Wen Zhang,
Yinming Liang,
Hui Wang
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s327858
Subject(s) - endocrinology , medicine , adipose tissue , lipid metabolism , coactivator , steatosis , inflammation , biology , metabolism , immune system , transcription factor , immunology , biochemistry , gene
Transcriptional coactivator B-cell lymphoma-3 (BCL3) is a member of the IκB family of NF-κB inhibitors and regulates the activity of the NF-κB pathway. However, the relationship between BCL3 and lipid metabolism remains unclear. The present study investigates the effects of BCL3 in immune and metabolism in obese mice.